产品名称
ACOX3 Rabbit Polyclonal Antibody
蛋白名称
Peroxisomal acyl-coenzyme A oxidase 3 (EC 1.3.3.6) (Branched-chain acyl-CoA oxidase) (BRCACox) (Pristanoyl-CoA oxidase)
反应种属
Human,Rat,Mouse,,Bovine
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
O15254
Human Swissprot Link
https://www.uniprot.org/uniprotkb/O15254/entry
Mouse Swissprot No.
Q9EPL9
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9EPL9
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q63448
免疫原
Synthesized peptide derived from human protein . at AA range: 480-560
特异性
ACOX3 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
Acyl-Coenzyme A oxidase 3 also know as pristanoyl -CoA oxidase (ACOX3)is involved in the desaturation of 2-methyl branched fatty acids in peroxisomes. Unlike the rat homolog, the human gene is expressed in very low amounts in liver such that its mRNA was undetectable by routine Northern-blot analysis or its product by immunoblotting or by enzyme activity measurements. However the human cDNA encoding a 700 amino acid protein with a peroxisomal targeting C-terminal tripeptide S-K-L was isolated and is thought to be expressed under special conditions such as specific developmental stages or in a tissue specific manner in tissues that have not yet been examined. [provided by RefSeq, Jul 2008],
信号通路
Fatty acid metabolism;alpha-Linolenic acid metabolism;Biosynthesis of unsaturated fatty acids;PPAR;
功能
catalytic activity:Acyl-CoA + O(2) = trans-2,3-dehydroacyl-CoA + H(2)O(2).,cofactor:FAD.,function:Oxidizes the CoA-esters of 2-methyl-branched fatty acids.,pathway:Lipid metabolism; peroxisomal fatty acid beta-oxidation.,similarity:Belongs to the acyl-CoA oxidase family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
