BD-PB2498-FGG Rabbit Polyclonal Antibody (C-term)-现货抗体产品库武汉枢密脑科学技术有限公司

FGG Rabbit Polyclonal Antibody (C-term)

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产品基本信息

产品货号

BD-PB2498

产品名称

FGG Rabbit Polyclonal Antibody (C-term)

别名

Fibrinogen gamma chain, FGG

类别

常规抗体

推荐应用

反应种属

Human

Human Gene ID

NP_000500.2;NP_068656.2

Human Swissprot No.

P02679

特异性

This FGG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 417-445 amino acids from the C-terminal region of human FGG.

稀释度

WB~~1:1000;IHC-P~~1:100~500;FC~~1:10~50

预测分子量

52kDa

同种型

Rabbit Ig

背景介绍

FGG is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this protein lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia.

组织表达

Detected in blood plasma (at protein level).

细胞定位

Secreted

期货

现货

纯化

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

FGG Antibody (C-term) western blot analysis in human blood plasma cell line lysates (35ug/lane).This demonstrates the FGG antibody detected the FGG protein (arrow).

FGG Antibody (C-term) IHC analysis in formalin fixed and paraffin embedded human hepatocarcinoma tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the FGG Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

FGG Antibody (C-term) flow cytometric analysis of T47D cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.