BD-PB2487-CAMK1G (CaMKI gamma) Rabbit Polyclonal Antibody (C-term)-现货抗体产品库武汉枢密脑科学技术有限公司

CAMK1G (CaMKI gamma) Rabbit Polyclonal Antibody (C-term)

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产品基本信息

产品货号

BD-PB2487

产品名称

CAMK1G (CaMKI gamma) Rabbit Polyclonal Antibody (C-term)

别名

Calcium/calmodulin-dependent protein kinase type 1G, CaM kinase I gamma, CaM kinase IG, CaM-KI gamma, CaMKI gamma, CaMKIG, CaMK-like CREB kinase III, CLICK III, CAMK1G, CLICK3, VWS1

类别

常规抗体

推荐应用

反应种属

Human

Human Gene ID

NP_065172.1

Human Swissprot No.

Q96NX5

特异性

This CAMK1G (CaMKI gamma) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 420-450 amino acids from the C-terminal region of human CAMK1G (CaMKI gamma).

稀释度

WB~~1:1000;IHC-P~~1:100~500

预测分子量

53kDa

同种型

Rabbit Ig

背景介绍

Ca2+/calmodulin-dependent protein kinase I (CaMKI) constitutes a family of closely related isoforms (alpha, beta and gamma). CLICK-III/CaMKIgamma is a novel membrane-anchored neuronal Ca2+/calmodulin-dependent protein kinase. AMKIgamma is abundant in neurons, particularly in the amygdala and ventromedial hypothalamus. Like the other CaMKI isoforms, full activation of CLICK-III/CaMKIgamma requires both Ca(2+)/CaM and phosphorylation by CaMKK.

组织表达

Mainly expressed in brain with small amounts in skeletal muscles, kidney, spleen and liver. Strongly expressed in forebrain neocortex, striatum and limbic system

细胞定位

Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein

期货

现货

纯化

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Western blot analysis of anti-CAMK 1G Pab in NCI-H460 cell lysate. CAMK 1G (arrow) was detected using purified Pab. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.

Western blot analysis of CAMK1G (arrow) using rabbit polyclonal CAMK1G Antibody (C-term) either nontransfected (Lane 1) or transiently transfected with the CAMK1G gene (Lane 2) .

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.