BD-PB2479-PANK3 Rabbit Polyclonal Antibody (N-term)-现货抗体产品库武汉枢密脑科学技术有限公司

PANK3 Rabbit Polyclonal Antibody (N-term)

产品详情相关文献产品问答相关产品

产品基本信息

产品货号

BD-PB2479

产品名称

PANK3 Rabbit Polyclonal Antibody (N-term)

别名

Pantothenate kinase 3, hPanK3, Pantothenic acid kinase 3, PANK3

类别

常规抗体

推荐应用

反应种属

Human

Human Gene ID

NP_078870.1

Human Swissprot No.

Q9H999

特异性

This PANK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human PANK3.

稀释度

WB~~1:1000;IHC-P~~1:100~500

预测分子量

41kDa

同种型

Rabbit Ig

背景介绍

PANK3 belongs to the pantothenate kinase family. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by CoA. This family member is expressed most abundantly in the liver.

组织表达

Highly expressed in the liver.

细胞定位

Cytoplasm {ECO:0000269|PubMed:23152917, ECO:0000305}

期货

现货

纯化

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Western blot analysis of anti-PANK3 Antibody (N-term) in NCI-H460 cell line lysates (35ug/lane). PANK3(arrow) was detected using the purified Pab.

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.