BD-PB2477-AMHR2 Rabbit Polyclonal Antibody (N-term R80)-现货抗体产品库武汉枢密脑科学技术有限公司

AMHR2 Rabbit Polyclonal Antibody (N-term R80)

产品详情相关文献产品问答相关产品

产品基本信息

产品货号

BD-PB2477

产品名称

AMHR2 Rabbit Polyclonal Antibody (N-term R80)

别名

Anti-Muellerian hormone type-2 receptor, Anti-Muellerian hormone type II receptor, AMH type II receptor, MIS type II receptor, MISRII, MRII, AMHR2, AMHR, MISR2

类别

常规抗体

推荐应用

反应种属

Human, Rat, Mouse

Human Gene ID

NP_001158162.1;NP_001158163.1;NP_065434.1

Human Swissprot No.

Q16671

特异性

This AMHR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 65-91 amino acids from the N-terminal region of human AMHR2.

稀释度

IHC-P-Leica~~1:500;WB~~1:500

预测分子量

63kDa

同种型

Rabbit Ig

背景介绍

The AMH receptor (AMHR or AMHR2) is a serine/threonine kinase with a single transmembrane domain belonging to the family of type II receptors for TGF-beta-related proteins. Anti-Mullerian hormone (AMH) and its receptor are involved in the regression of Mullerian ducts in male fetuses. Male sex differentiation is mediated by 2 discrete hormones produced by the fetal testis. Testosterone, produced by Leydig cells, virilizes the external genitalia and promotes prostatic growth; anti-Mullerian hormone (AMH) results in regression of Mullerian ducts which would otherwise differentiate into the uterus and fallopian tubes.

细胞定位

Membrane; Single-pass type I membrane protein.

期货

现货

纯化

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunohistochemical analysis of paraffin-embedded Human testis tissue using BD-PB2477 performed on the Leica® BOND RXm. Tissue was fixed with formaldehyde at room temperature, antigen retrieval was by heat mediation with a EDTA buffer (pH9. 0). Samples were incubated with primary antibody(1:500) for 1 hours at room temperature. A undiluted biotinylated CRF Anti-Polyvalent HRP Polymer antibody was used as the secondary antibody.

All lanes : Anti-AMHR2 Antibody (N-term) at 1:500 dilution Lane 1: OVCAR3 whole cell lysate Lane 2: SK-OV-3 whole cell lysate Lane 3: MDA-MB-231 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 63 kDa Blocking/Dilution buffer: 5% NFDM/TBST.