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AK7 Rabbit Polyclonal Antibody (C-term)

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产品基本信息

产品货号
BD-PB2469
产品名称
AK7 Rabbit Polyclonal Antibody (C-term)
别名
Adenylate kinase 7, AK 7, ATP-AMP transphosphorylase 7, AK7
类别
常规抗体
推荐应用
WB
反应种属
Human
Human Gene ID
NP_689540.2
Human Swissprot No.
Q96M32
特异性
This AK7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 629-656 amino acids from the C-terminal region of human AK7.
稀释度
WB~~1:1000;IHC-P~~1:100~500
预测分子量
83kDa
同种型
Rabbit Ig
背景介绍
The adenylate kinases (AK) are a family of structurally and functionally related enzymes that catalyze a similar reaction, MgNTP + AMP = MgNDP + ADP (N = A or G). The AK enzymes are important for maintenance of homeostasis of the adenine and guanine nucleotide pools. AK1 is a cytosolic enzyme for which ATP is the substrate. AK2 catalyzes the same reaction as AK1, but it is localized in the mitochondrial intermembrane space. AK3 is present in the mitochondrial matrix and prefers GTP over ATP as the substrate.
组织表达
Expressed in sperm and airway epithelial cells (at protein level).
细胞定位
Cytoplasm, cytosol. Cell projection, cilium, flagellum Note=Detected along the full length of sperm flagellum, where it colocalizes with alpha-tubulin.
期货
现货
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Western blot analysis of anti-AK7 Antibody (C-term) in K562 cell line lysates (35ug/lane).AK7(arrow) was detected using the purified Pab.

AK7 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human skin carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the AK7 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

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