BD-PB2459-CBS Rabbit Polyclonal Antibody (Center)-现货抗体产品库武汉枢密脑科学技术有限公司

CBS Rabbit Polyclonal Antibody (Center)

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产品基本信息

产品货号

BD-PB2459

产品名称

CBS Rabbit Polyclonal Antibody (Center)

别名

Cystathionine beta-synthase, Beta-thionase, Serine sulfhydrase, CBS

类别

常规抗体

推荐应用

反应种属

Human, Mouse, Rat

Human Gene ID

NP_000062.1;NP_001171479.1;NP_001171480.1

Human Swissprot No.

P35520

特异性

This CBS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 301-330 amino acids from the Central region of human CBS.

稀释度

WB~~1:500

预测分子量

61kDa

同种型

Rabbit Ig

背景介绍

CBS acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. This protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria.

组织表达

In the adult strongly expressed in liver and pancreas, some expression in heart and brain, weak expression in lung and kidney. In the fetus, expressed in brain, liver and kidney

细胞定位

Cytoplasm. Nucleus

期货

现货

纯化

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

All lanes : Anti-CBS Antibody (Center) at 1:500 dilution Lane 1: Hela whole cell lysate Lane 2: MCF-7 whole cell lysate Lane 3: LNCap whole cell lysate Lane 4: mouse liver lysate Lane 5: mouse pancreas lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 61 kDa Blocking/Dilution buffer: 5% NFDM/TBST.