产品名称
PAX6-T373 Rabbit Polyclonal Antibody
别名
Paired box protein Pax-6, Aniridia type II protein, Oculorhombin, PAX6, AN2
Human Gene ID
NP_000271.1;NP_001121084.1;NP_001245393.1;NP_001245394.1;NP_001595.2
Human Swissprot No.
P26367
特异性
This PAX6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 352-380 amino acids from human PAX6.
背景介绍
PAX6 encodes paired box gene 6, one of many human homologs of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA, and function as regulators of gene transcription. This gene is expressed in the developing nervous system, and in developing eyes. Mutations in this gene are known to cause ocular disorders such as aniridia and Peter's anomaly.
组织表达
[Isoform 1]: Expressed in lymphoblasts.
细胞定位
Nucleus {ECO:0000250|UniProtKB:P63015}. [Isoform 5a]: Nucleus {ECO:0000250|UniProtKB:P63016}
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
