产品名称
RBBP9 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/10741
Human Swissprot No.
O75884
Human Swissprot Link
https://www.uniprot.org/uniprotkb/O75884/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/26450
Mouse Swissprot No.
O88851
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/O88851
Rat Gene Link
https://www.uniprot.org/uniprot/29459
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/O88350
免疫原
Synthesized peptide derived from human RBBP9 AA range: 108-158
特异性
This antibody detects endogenous levels of RBBP9 at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is a retinoblastoma binding protein that may play a role in the regulation of cell proliferation and differentiation. Two alternatively spliced transcript variants of this gene with identical predicted protein products have been reported, one of which is a nonsense-mediated decay candidate. [provided by RefSeq, Jul 2008],
组织表达
Expressed at higher levels in tumor tissues such as carcinoma.
细胞定位
nucleus,nucleolus,cytoplasm,extracellular exosome,
功能
function:May play a role in the transformation process due to its capacity to confer resistance to the growth-inhibitory effects of TGF-beta1 through interaction with retinoblastoma and the subsequent displacement of E2F-1.,similarity:Belongs to the RBBP9 family.,tissue specificity:Widely expressed. Expressed at higher levels in tumor tissues than in normal tissues.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
