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GNAS Rabbit Polyclonal Antibody (Center)

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产品基本信息

产品货号
BD-PB2450
产品名称
GNAS Rabbit Polyclonal Antibody (Center)
别名
Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas, Adenylate cyclase-stimulating G alpha protein, Extra large alphas protein, XLalphas, GNAS, GNAS1 {ECO:0000303|PubMed:9707596}
类别
常规抗体
推荐应用
WB
反应种属
Human
Human Gene ID
NP_536350.2
Human Swissprot No.
Q5JWF2
特异性
This GNAS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 640-667 amino acids from the Central region of human GNAS.
稀释度
WB~~1:4000
预测分子量
111kDa
同种型
Rabbit Ig
背景介绍
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(s) protein is involved in hormonal regulation of adenylate cyclase: it activates the cyclase in response to beta-adrenergic stimuli. XLas isoforms interact with the same set of receptors as Gnas isoforms.
细胞定位
Cell membrane; Peripheral membrane protein {ECO:0000250|UniProtKB:Q63803}. Apical cell membrane
期货
现货
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Anti-GNAS Antibody (Center) at 1:4000 dilution + Ramos whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 111 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

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