BD-PB2434-GBAS Rabbit Polyclonal Antibody (Center)-现货抗体产品库武汉枢密脑科学技术有限公司

GBAS Rabbit Polyclonal Antibody (Center)

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产品基本信息

产品货号

BD-PB2434

产品名称

GBAS Rabbit Polyclonal Antibody (Center)

别名

Protein NipSnap homolog 2, NipSnap2, Glioblastoma-amplified sequence, GBAS, NIPSNAP2

类别

常规抗体

推荐应用

反应种属

Human

Human Gene ID

NP_001189398.1;NP_001474.1

Human Swissprot No.

O75323

特异性

This GBAS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 130-159 amino acids from the Central region of human GBAS.

稀释度

WB~~1:1000;IHC-P~~1:100~500;FC~~1:10~50

预测分子量

34kDa

同种型

Rabbit Ig

背景介绍

Chromosomal region 7p12, which contains GBAS, is amplified in approximately 40% of glioblastomas, the most common and malignant form of central nervous system tumor.The predicted 286-amino acid protein contains a signal peptide, a transmembrane domain, and 2 tyrosine phosphorylation sites. The GBAS transcript is expressed most abundantly in heart and skeletal muscle. GBAS protein might be involved in vesicular transport.

组织表达

Widely expressed. Most abundant in heart and skeletal muscle

细胞定位

Cytoplasm {ECO:0000250|UniProtKB:O55126}. Mitochondrion outer membrane

期货

现货

纯化

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Western blot analysis of GBAS Antibody (Center) in Ramos cell line lysates (35ug/lane).GBAS (arrow) was detected using the purified Pab.

GBAS Antibody (Center) IHC analysis in formalin fixed and paraffin embedded skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the GBAS Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

GBAS Antibody (Center) flow cytometric analysis of Ramos cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.