BD-PB2420-PDIA6 Rabbit Polyclonal Antibody (Center D251)-现货抗体产品库武汉枢密脑科学技术有限公司

PDIA6 Rabbit Polyclonal Antibody (Center D251)

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产品基本信息

产品货号

BD-PB2420

产品名称

PDIA6 Rabbit Polyclonal Antibody (Center D251)

别名

Protein disulfide-isomerase A6, Endoplasmic reticulum protein 5, ER protein 5, ERp5, Protein disulfide isomerase P5, Thioredoxin domain-containing protein 7, PDIA6, ERP5, P5, TXNDC7

类别

常规抗体

推荐应用

反应种属

Human

Human Gene ID

NP_005733.1

Human Swissprot No.

Q15084

特异性

This PDIA6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 236-264 amino acids from the Central region of human PDIA6.

稀释度

WB~~1:1000;IHC-P~~1:100~500;FC~~1:10~50

预测分子量

48kDa

同种型

Rabbit Ig

背景介绍

Protein disulfide isomerases (EC 5.3.4.1), such as PDIA6, are endoplasmic reticulum (ER) resident proteins that catalyze formation, reduction, and isomerization of disulfide bonds in proteins and are thought to play a role in folding of disulfide-bonded proteins.

组织表达

Expressed in platelets (at protein level).

细胞定位

Endoplasmic reticulum lumen. Cell membrane. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:12643545)

期货

现货

纯化

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Western blot analysis of PDIA6 Antibody (Center D251) in NCI-H460, MCF-7, A2058 cell line lysates (35ug/lane). PDIA6 (arrow) was detected using the purified Pab.

Formalin-fixed and paraffin-embedded human brain tissue reacted with PDIA6 Antibody (Center D251), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Flow cytometric analysis of hela cells using PDIA6 Antibody (Center D251)(bottom histogram) compared to a negative control cell (top histogram)FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.