产品名称
AOAH Rabbit Polyclonal Antibody
蛋白名称
Acyloxyacyl hydrolase (EC 3.1.1.77) [Cleaved into: Acyloxyacyl hydrolase small subunit; Acyloxyacyl hydrolase large subunit]
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
P28039
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P28039/entry
Mouse Swissprot No.
O35298
Mouse Swissprot Link
http://www.uniprot.org/uniprot/O35298
免疫原
Synthesized peptide derived from human protein . at AA range: 260-340
特异性
AOAH Polyclonal Antibody detects endogenous levels of protein.
宿主
Polyclonal, Rabbit,IgG
背景介绍
This locus encodes both the light and heavy subunits of acyloxyacyl hydrolase. The encoded enzyme catalyzes the hydrolysis of acyloxylacyl-linked fatty acyl chains from bacterial lipopolysaccharides, effectively detoxifying these molecules. The encoded protein may play a role in modulating host inflammatory response to gram-negative bacteria. Alternatively spliced transcript variants have been described.[provided by RefSeq, Apr 2010],
组织表达
Pancreas,Synovial cell,
细胞定位
Secreted . Cytoplasmic vesicle . Detected in urine. .
功能
catalytic activity:3-(acyloxy)acyl group of bacterial toxin = 3-hydroxyacyl group of bacterial toxin + a fatty acid.,function:Removes the secondary (acyloxyacyl-linked) fatty acyl chains from the lipid A region of bacterial lipopolysaccharides.,PTM:Both subunits contain a number of cysteine residues that may form disulfide bridges.,similarity:Contains 1 saposin B-type domain.,subunit:Heterodimer.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
