产品名称
ACSA Rabbit Polyclonal Antibody
蛋白名称
Acetyl-coenzyme A synthetase, cytoplasmic (EC 6.2.1.1) (Acetate--CoA ligase) (Acetyl-CoA synthetase) (ACS) (AceCS) (Acyl-CoA synthetase short-chain family member 2) (Acyl-activating enzyme)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q9NR19
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9NR19/entry
Mouse Swissprot No.
Q9QXG4
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9QXG4
免疫原
Synthesized peptide derived from human protein . at AA range: 40-120
特异性
ACSA Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a cytosolic enzyme that catalyzes the activation of acetate for use in lipid synthesis and energy generation. The protein acts as a monomer and produces acetyl-CoA from acetate in a reaction that requires ATP. Expression of this gene is regulated by sterol regulatory element-binding proteins, transcription factors that activate genes required for the synthesis of cholesterol and unsaturated fatty acids. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2009],
组织表达
Blood,Melanoma,Muscle,Platelet,Skin,Tongue,
细胞定位
Cytoplasm, cytosol .
信号通路
Glycolysis / Gluconeogenesis;Pyruvate metabolism;Propanoate metabolism;
功能
catalytic activity:ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA.,function:Activates acetate so that it can be used for lipid synthesis or for energy generation.,similarity:Belongs to the ATP-dependent AMP-binding enzyme family.,subunit:Monomer.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
