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CRAT Rabbit Polyclonal Antibody (N-term)

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产品基本信息

产品货号
BD-PB2403
产品名称
CRAT Rabbit Polyclonal Antibody (N-term)
别名
Carnitine O-acetyltransferase, Carnitine acetylase, Carnitine acetyltransferase, CAT, CrAT, CRAT, CAT1
类别
常规抗体
推荐应用
WB
反应种属
Human
Human Gene ID
NP_000746.2;NP_001244292.1
Human Swissprot No.
P43155
特异性
This CRAT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-96 amino acids from the N-terminal region of human CRAT.
稀释度
WB~~1:1000;IHC-P~~1:100~500
预测分子量
71kDa
同种型
Rabbit Ig
背景介绍
CRAT is carnitine acetyltransferase (CRAT), which is a key enzyme in the metabolic pathway in mitochondria, peroxisomes and endoplasmic reticulum. CRAT catalyzes the reversible transfer of acyl groups from an acyl-CoA thioester to carnitine and regulates the ratio of acylCoA/CoA in the subcellular compartments.
组织表达
Mostly in skeletal muscle, less in heart, liver and pancreas, only weakly detectable in brain, placenta, lung and kidney
细胞定位
Endoplasmic reticulum. Peroxisome. Mitochondrion inner membrane; Peripheral membrane protein; Matrix side [Isoform 2]: Peroxisome
期货
现货
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Western blot analysis of CRAT antibody (N-term) in CEM cell line lysates (35ug/lane). CRAT (arrow) was detected using the purified Pab.

CRAT Antibody (N-term) IHC analysis in formalin fixed and paraffin embedded human Skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CRAT Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

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