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MLLT1 Rabbit Polyclonal Antibody (C-term)

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产品基本信息

产品货号
BD-PB2370
产品名称
MLLT1 Rabbit Polyclonal Antibody (C-term)
别名
Protein ENL, YEATS domain-containing protein 1, MLLT1, ENL, LTG19, YEATS1
类别
常规抗体
推荐应用
WB
反应种属
Human
Human Gene ID
NP_005925.2
Human Swissprot No.
Q03111
特异性
This MLLT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 523-552 amino acids from the C-terminal region of human MLLT1.
稀释度
WB~~1:1000
预测分子量
62kDa
同种型
Rabbit Ig
背景介绍
Chromosome band 11q23 is the site of translocations in myeloid and lymphoid acute leukemias, pediatric leukemias, and treatment-induced secondary acute myelogenous leukemia. The translocation breakpoints cluster in a restricted region of the HRX gene resulting in chimeric genes that encode an N-terminal portion of Hrx fused to various partner proteins. Myeloid/lymphoid or mixed-lineage leukemia translocated to 1 (MLLT1) is a nuclear protein with transcriptional transactivation properties that is fused to Hrx in t(11;19) leukemias. The minimal MLLT1 sequence required for transcription activation was narrowed to the C-terminal 90 amino acids.
细胞定位
Nucleus.
期货
现货
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Western blot analysis of anti-MLLT1 Pab in A257 cell line lysate (35ug/lane). MLLT1(arrow) was detected using the purified Pab.

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