BD-PB2282-SRD5A3 Rabbit Polyclonal Antibody (C-term)-现货抗体产品库武汉枢密脑科学技术有限公司

SRD5A3 Rabbit Polyclonal Antibody (C-term)

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产品基本信息

产品货号

BD-PB2282

产品名称

SRD5A3 Rabbit Polyclonal Antibody (C-term)

别名

Polyprenol reductase, 3-oxo-5-alpha-steroid 4-dehydrogenase 3, Steroid 5-alpha-reductase 2-like, Steroid 5-alpha-reductase 3, S5AR 3, SR type 3, SRD5A3, SRD5A2L

类别

常规抗体

推荐应用

反应种属

Human, Rat

Human Gene ID

NP_078868.1

Human Swissprot No.

Q9H8P0

特异性

This SRD5A3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 283-311 amino acids from the C-terminal region of human SRD5A3.

稀释度

WB~~1:1000;IHC-P~~1:100~500;FC~~1:10~50

预测分子量

37kDa

同种型

Rabbit Ig

背景介绍

SRD5A3 converts testosterone (T) into 5-alpha-dihydrotestosterone (DHT).

组织表达

Expressed in preadipocytes (at protein level) (PubMed:26855069). Overexpressed in hormone-refractory prostate cancers (HRPC). Almost no or little expression in normal adult organs

细胞定位

Endoplasmic reticulum membrane; Multi-pass membrane protein

期货

现货

纯化

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

SRD5A3 Antibody (C-term) western blot analysis in 293,LNCaP,PC-3,NCI-H292 cell line lysates (35ug/lane).This demonstrates the SRD5A3 antibody detected the SRD5A3 protein (arrow).

SRD5A3 Antibody (C-term) IHC analysis in formalin fixed and paraffin embedded human prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the SRD5A3 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

SRD5A3 Antibody (C-term) flow cytometric analysis of K562 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.