BD-PB2272-GMNN Rabbit Polyclonal Antibody (Center Y111)-现货抗体产品库武汉枢密脑科学技术有限公司

GMNN Rabbit Polyclonal Antibody (Center Y111)

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产品基本信息

产品货号

BD-PB2272

产品名称

GMNN Rabbit Polyclonal Antibody (Center Y111)

别名

Geminin, GMNN

类别

常规抗体

推荐应用

反应种属

Human

Human Gene ID

NP_001238918.1;NP_001238919.1;NP_001238920.1;NP_056979.1

Human Swissprot No.

O75496

特异性

This GMNN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 96-123 amino acids from the Central region of human GMNN.

稀释度

WB~~1:1000;IHC-P~~1:100~500

预测分子量

24kDa

同种型

Rabbit Ig

背景介绍

GMNN inhibits DNA replication by preventing the incorporation of MCM complex into prereplication complex (pre-RC). It is degraded during the mitotic phase of the cell cycle. Its destruction at the metaphase-anaphase transition permits replication in the succeeding cell cycle.

细胞定位

Cytoplasm. Nucleus. Note=Mainly cytoplasmic but can be relocalized to the nucleus.

期货

现货

纯化

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Western blot analysis of GMNN Antibody (Center Y111) in HepG2 cell line lysates (35ug/lane).GMNN (arrow) was detected using the purified Pab.

GMNN Antibody (Center Y111) IHC analysis in formalin fixed and paraffin embedded lung tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the GMNN Antibody (Center Y111) for immunohistochemistry. Clinical relevance has not been evaluated.