BD-PB2266-CNO6L Rabbit Polyclonal Antibody (C-term)-现货抗体产品库武汉枢密脑科学技术有限公司

CNO6L Rabbit Polyclonal Antibody (C-term)

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产品基本信息

产品货号

BD-PB2266

产品名称

CNO6L Rabbit Polyclonal Antibody (C-term)

别名

CNOT6L; CCR4B; CCR4-NOT transcription complex subunit 6-like; Carbon catabolite repressor protein 4 homolog B

类别

常规抗体

推荐应用

反应种属

Human

Human Gene ID

NP_653172.2

Human Swissprot No.

Q96LI5

特异性

This CNO6L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 414-442 amino acids from the C-terminal region of human CNO6L.

稀释度

IHC-P~~1:100~500;WB~~1:1000

预测分子量

63kDa

同种型

Rabbit Ig

背景介绍

CNO6L plays a role in the deadenylation of mRNAs in the cytoplasm. CNO6L has 3'-5' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. CNO6L may be involved in the deadenylation-dependent degradation of mRNAs through the 3'-UTR AU-rich element-mediated mechanism. This protein involved in deadenylation-dependent degradation of CDKN1B mRNA.

组织表达

Highly expressed in placenta, skeletal muscle, pancreas, testis and leukocytes. Weakly expressed in heart, spleen and thymus.

细胞定位

Cytoplasm. Nucleus Note=Predominantly cytoplasmic.

期货

现货

纯化

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

CNO6L Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CNO6L Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

CNO6L Antibody (C-term) western blot analysis in Sk-Br-3 cell line tissue lysates (35ug/lane).This demonstrates the CNO6L antibody detected the CNO6L protein (arrow).