BD-PB2258-LINGO-1(LRRN6A)-S596 (C-term) Rabbit Polyclonal Antibody-现货抗体产品库武汉枢密脑科学技术有限公司

LINGO-1(LRRN6A)-S596 (C-term) Rabbit Polyclonal Antibody

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产品基本信息

产品货号

BD-PB2258

产品名称

LINGO-1(LRRN6A)-S596 (C-term) Rabbit Polyclonal Antibody

别名

Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1, Leucine-rich repeat neuronal protein 1, Leucine-rich repeat neuronal protein 6A, Lingo1, Lern1, Lrrn6a

类别

常规抗体

推荐应用

反应种属

Human, Mouse

Human Swissprot No.

Q9D1T0

Mouse Gene ID

NP_851419.1

特异性

This LINGO-1(LRRN6A) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 575-603 amino acids from the C-terminal region of human LINGO-1(LRRN6A).

稀释度

WB~~1:1000-1:2000

预测分子量

69kDa

同种型

Rabbit Ig

背景介绍

LINGO-1 is functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors. LINGO-1 is also an important negative regulator of oligodentrocyte differentiation and axonal myelination.

组织表达

Highly specific expression in the central nervous system. Predominant expression in neocortex, amygdala, hippocampus, thalamus and entorhinal cortex, with lower levels in cerebellum and basal nuclei.

细胞定位

Cell membrane; Single-pass type I membrane protein

期货

现货

纯化

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

All lanes : Anti-LINGO-1(LRRN6A)-S596 (C-term) Antibody at 1:1000-1:2000 dilution Lane 1: Mouse brain lysate Lane 2: Mouse cerebellum lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 69 kDa Blocking/Dilution buffer: 5% NFDM/TBST.