BD-PB2257-G6PD Rabbit Polyclonal Antibody (Center)-现货抗体产品库武汉枢密脑科学技术有限公司

G6PD Rabbit Polyclonal Antibody (Center)

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产品基本信息

产品货号

BD-PB2257

产品名称

G6PD Rabbit Polyclonal Antibody (Center)

别名

Glucose-6-phosphate 1-dehydrogenase, G6PD, G6PD

类别

常规抗体

推荐应用

反应种属

Human

Human Gene ID

NP_000393.4;NP_001035810.1

Human Swissprot No.

P11413

特异性

This G6PD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 297-326 amino acids from the Central region of human G6PD.

稀释度

WB~~1:1000;IHC-P~~1:100~500;FC~~1:10~50

预测分子量

59kDa

同种型

Rabbit Ig

背景介绍

G6PD encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia.

组织表达

Isoform Long is found in lymphoblasts, granulocytes and sperm

细胞定位

Cytoplasm, cytosol. Membrane; Peripheral membrane protein

期货

现货

纯化

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Western blot analysis of G6PD Antibody (Center) in K562,MCF-7 cell line lysates (35ug/lane).G6PD (arrow) was detected using the purified Pab.

G6PD Antibody (Center) IHC analysis in formalin fixed and paraffin embedded testis followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the G6PD Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

G6PD Antibody (Center) flow cytometric analysis of MCF-7 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.