BD-PB2254-PAAF1 Rabbit Polyclonal Antibody (N-term)-现货抗体产品库武汉枢密脑科学技术有限公司

PAAF1 Rabbit Polyclonal Antibody (N-term)

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产品基本信息

产品货号

BD-PB2254

产品名称

PAAF1 Rabbit Polyclonal Antibody (N-term)

别名

Proteasomal ATPase-associated factor 1, Protein G-16, WD repeat-containing protein 71, PAAF1, WDR71

类别

常规抗体

推荐应用

反应种属

Human

Human Gene ID

NP_001254732.1;NP_001254733.1;NP_001254734.1;NP_001254735.1;NP_079431.1

Human Swissprot No.

Q9BRP4

特异性

This PAAF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 109-138 amino acids from the N-terminal region of human PAAF1.

稀释度

WB~~1:1000;IHC-P~~1:100~500

预测分子量

42kDa

同种型

Rabbit Ig

背景介绍

PAAF1 inhibits proteasome 26S assembly and proteolytic activity by impairing the association of the 19S regulatory complex with the 20S core. In case of HIV-1 infection, recruited by viral Tat to the HIV-1 promoter, where it promotes the recruitment of 19S regulatory complex through dissociation of the proteasome 26S. This presumably promotes provirus transcription efficiency.

组织表达

Ubiquitously expressed, with highest levels in kidney, brain and testis.

期货

现货

纯化

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Western blot analysis of PAAF1 Antibody (N-term) in A549 cell line lysates (35ug/lane).PAAF1 (arrow) was detected using the purified Pab.

PAAF1 Antibody (N-term) IHC analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the PAAF1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.