BD-PB2230-GSDMA Rabbit Polyclonal Antibody (N-term)-现货抗体产品库武汉枢密脑科学技术有限公司

GSDMA Rabbit Polyclonal Antibody (N-term)

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产品基本信息

产品货号

BD-PB2230

产品名称

GSDMA Rabbit Polyclonal Antibody (N-term)

别名

Gasdermin-A, Gasdermin-1, GSDMA, GSDM, GSDM1

类别

常规抗体

推荐应用

反应种属

Human, Mouse

Human Gene ID

NP_835465.2

Human Swissprot No.

Q96QA5

特异性

This GSDMA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-94 amino acids from the N-terminal region of human GSDMA.

稀释度

WB~~1:1000;IHC-P~~1:100~500;FC~~1:10~50

预测分子量

49kDa

同种型

Rabbit Ig

背景介绍

GSDMA induces apoptosis.

组织表达

Expressed predominantly in the gastrointestinal tract and, at a lower level, in the skin. Also detected in mammary gland. In the gastrointestinal tract, mainly expressed in differentiated cells, including the differentiated cell layer of esophagus and mucus-secreting pit cells of the gastric epithelium Down-regulateded in gastric cancer cells.

细胞定位

[Gasdermin-A]: Cytoplasm, perinuclear region. Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q5Y4Y6}

期货

现货

纯化

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Western blot analysis of GSDMA Antibody (N-term) in mouse liver tissue lysates (35ug/lane). GSDMA (arrow) was detected using the purified Pab.

GSDMA Antibody (N-term) IHC analysis in formalin fixed and paraffin embedded human skin carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the GSDMA Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

GSDMA Antibody (N-term) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.