BD-PB2216-CJ119 Rabbit Polyclonal Antibody (N-term)-现货抗体产品库武汉枢密脑科学技术有限公司

CJ119 Rabbit Polyclonal Antibody (N-term)

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产品基本信息

产品货号

BD-PB2216

产品名称

CJ119 Rabbit Polyclonal Antibody (N-term)

别名

Mini-chromosome maintenance complex-binding protein, MCM-BP, MCM-binding protein, MCMBP, C10orf119

类别

常规抗体

推荐应用

反应种属

Human

Human Gene ID

NP_001243307.1;NP_001243308.1;NP_079110.1

Human Swissprot No.

Q9BTE3

特异性

This CJ119 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 143-171 amino acids from the N-terminal region of human CJ119.

稀释度

WB~~1:1000;IHC-P~~1:100~500;FC~~1:10~50

预测分子量

73kDa

同种型

Rabbit Ig

背景介绍

CJ119 is a carefully orchestrated process involving many proteins that assemble at origins of replication. Among these are the 6 proteins of the minichromosome maintenance (MCM) complex (e.g., MCM2; MIM 116945), which form a hexamer. Each MCM subunit performs an essential function in initiation and elongation of DNA replication. MCMBP can replace MCM2 in the MCM complex, thus forming an alternative MCM hexamer.

细胞定位

Nucleus. Note=Associates with chromatin. Highly associated with chromatin in G1/S and S phases, reduced binding to chromatin in G2, and further decreased binding in early M phase. It then reassociates with chromatin in late M phase. Dissociates from chromatin later than component of the MCM complex

期货

现货

纯化

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Western blot analysis of CJ119 Antibody (N-term) in MDA-MB231 cell line lysates (35ug/lane). CJ119 (arrow) was detected using the purified Pab.

CJ119 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human cervix carcinoma tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CJ119 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

CJ119 Antibody (N-term) flow cytometric analysis of MDA-MB231 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.