产品名称
S47A2 Rabbit Polyclonal Antibody (N-term)
别名
Multidrug and toxin extrusion protein 2, MATE-2, hMATE-2, Kidney-specific H(+)/organic cation antiporter, Solute carrier family 47 member 2, SLC47A2, MATE2
Human Gene ID
NP_001093116.1;NP_001243592.1;NP_690872.2
Human Swissprot No.
Q86VL8
特异性
This S47A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 125-153 amino acids from the N-terminal region of human S47A2.
背景介绍
S47A2 belongs to a family of transporters involved in excretion of toxic electrolytes, both endogenous and exogenous, through urine and bile. This transporter family shares homology with the bacterial MATE (multidrug and toxin extrusion) protein family responsible for drug resistance. This gene is one of two members of the MATE transporter family located near each other on chromosome 17.
组织表达
Isoform 3 is predominantly expressed in kidney. Isoform 6 is expressed in brain.
细胞定位
Cell membrane; Multi-pass membrane protein. Note=Localized at the brush border membranes of the proximal tubules
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
