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Phospho-RAD9(Y28) Rabbit Polyclonal Antibody

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产品基本信息

产品货号
BD-PB2144
产品名称
Phospho-RAD9(Y28) Rabbit Polyclonal Antibody
别名
Cell cycle checkpoint control protein RAD9A, hRAD9, DNA repair exonuclease rad9 homolog A, RAD9A
类别
常规抗体
推荐应用
WB
反应种属
Human
Human Gene ID
NP_001230153.1;NP_004575.1
Human Swissprot No.
Q99638
特异性
This RAD9 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y28 of human RAD9.
稀释度
WB~~1:1000
预测分子量
43kDa
同种型
Rabbit Ig
背景介绍
Rad9 is highly similar to Schizosaccharomyces pombe rad9, a cell cycle checkpoint protein required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein is found to possess 3' to 5' exonuclease activity, which may contribute to its role in sensing and repairing DNA damage. It forms a checkpoint protein complex with RAD1 and HUS1. This complex is recruited by checkpoint protein RAD17 to the sites of DNA damage, which is thought to be important for triggering the checkpoint-signaling cascade.
细胞定位
Nucleus.
期货
现货
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is first purified by protein G affinity chromatography. Then, the antibody fraction is peptide affinity purified in a 2-step procedure with control and phosphor

The anti-Phospho-Rad9-Y28 Pab is used in Western blot to detect Phospho-Rad9-Y28 in HL60 tissue lysate

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