BD-PB2139-RBM14 Rabbit Polyclonal Antibody (Center)-现货抗体产品库武汉枢密脑科学技术有限公司

RBM14 Rabbit Polyclonal Antibody (Center)

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产品基本信息

产品货号

BD-PB2139

产品名称

RBM14 Rabbit Polyclonal Antibody (Center)

别名

RNA-binding protein 14, Paraspeckle protein 2, PSP2, RNA-binding motif protein 14, RRM-containing coactivator activator/modulator, Synaptotagmin-interacting protein, SYT-interacting protein, RBM14, SIP

类别

常规抗体

推荐应用

反应种属

Human

Human Gene ID

NP_001185765.1;NP_001185766.1;NP_001185774.1;NP_001185775.1;NP_006319.1

Human Swissprot No.

Q96PK6

特异性

This RBM14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 193-223 amino acids from the Central region of human RBM14.

稀释度

WB~~1:1000;IHC-P~~1:100~500;FC~~1:10~50

预测分子量

69kDa

同种型

Rabbit Ig

背景介绍

Isoform 1 may function as a nuclear receptor coactivator, enhancing transcription through other coactivators such as NCOA6 and CITED1. Isoform 2, functions as a transcriptional repressor, modulating transcriptional activities of coactivators including isoform 1, NCOA6 and CITED1.

组织表达

Expressed in all tissues tested, including brain, heart, skeletal muscle, colon, thymus, spleen, kidney, liver, small intestine, placenta, lung and peripheral blood lymphocytes

细胞定位

Nucleus. Nucleus, nucleolus. Cytoplasm. Note=In punctate subnuclear structures often located adjacent to splicing speckles, called paraspeckles (PubMed:11790299). Cytoplasmic localization is crucial for its function in suppressing the formation of aberrant centriolar protein complexes (PubMed:25385835).

期货

现货

纯化

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Western blot analysis of RBM14 Antibody (Center) in Jurkat cell line lysates (35ug/lane). RBM14 (arrow) was detected using the purified Pab.

Formalin-fixed and paraffin-embedded brain tissue reacted with RBM14 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

RBM14 Antibody (Center) flow cytometric analysis of Jurkat cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.