产品名称
RLA0 Rabbit Polyclonal Antibody
蛋白名称
60S acidic ribosomal protein P0 (60S ribosomal protein L10E)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
P05388
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P05388/entry
Mouse Swissprot No.
P14869
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P14869
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941P19945
免疫原
Synthesized peptide derived from human protein . at AA range: 240-320
特异性
RLA0 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein, which is the functional equivalent of the E. coli L10 ribosomal protein, belongs to the L10P family of ribosomal proteins. It is a neutral phosphoprotein with a C-terminal end that is nearly identical to the C-terminal ends of the acidic ribosomal phosphoproteins P1 and P2. The P0 protein can interact with P1 and P2 to form a pentameric complex consisting of P1 and P2 dimers, and a P0 monomer. The protein is located in the cytoplasm. Transcript variants derived from alternative splicing exist; they encode the same protein. As is typical for genes encoding ribosomal pro
组织表达
Adipose tissue,Brain,Cervix,Cervix carcinoma,Colon,Coronary
细胞定位
Nucleus . Cytoplasm . Localized in cytoplasmic mRNP granules containing untranslated mRNAs (PubMed:19188445, PubMed:17289661). .
功能
function:Ribosomal protein P0 is the functional equivalent of E.coli protein L10.,similarity:Belongs to the ribosomal protein L10P family.,subunit:P0 forms a pentameric complex by interaction with dimers of P1 and P2.,subunit:P0 forms a pentameric complex by interaction with dimers of P1 and P2. Interacts with Lassa virus Z protein.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
