BD-PB2126-CDA Rabbit Polyclonal Antibody (Center)-现货抗体产品库武汉枢密脑科学技术有限公司

CDA Rabbit Polyclonal Antibody (Center)

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产品基本信息

产品货号

BD-PB2126

产品名称

CDA Rabbit Polyclonal Antibody (Center)

别名

Cytidine deaminase, Cytidine aminohydrolase, CDA, CDD

类别

常规抗体

推荐应用

反应种属

Human, Rat, Mouse

Human Gene ID

NP_001776.1

Human Swissprot No.

P32320

特异性

This CDA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 51-83 amino acids from the Central region of human CDA.

稀释度

WB~~1:1000

预测分子量

16kDa

同种型

Rabbit Ig

背景介绍

CDA forms a homotetramer that catalyzes the irreversible hydrolytic deamination of cytidine and deoxycytidine to uridine and deoxyuridine, respectively. This protein is one of several deaminases responsible for maintaining the cellular pyrimidine pool. Mutations in the CDA gene are associated with decreased sensitivity to the cytosine nucleoside analogue cytosine arabinoside used in the treatment of certain childhood leukemias.

组织表达

Highly expressed in granulocytes while expression is very low in fibroblasts, chondrocytes, monocytes, and T- as well as B-cell lines

期货

现货

纯化

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Western blot analysis of lysates from Hela cell line, human liver and mouse kidney tissue lysate(from left to right), using CDA Antibody (Center). BD-PB2126 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 35ug per lane.