BD-PB2116-ITGB1BP3 Rabbit Polyclonal Antibody (N-term)-现货抗体产品库武汉枢密脑科学技术有限公司

ITGB1BP3 Rabbit Polyclonal Antibody (N-term)

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产品基本信息

产品货号

BD-PB2116

产品名称

ITGB1BP3 Rabbit Polyclonal Antibody (N-term)

别名

Nicotinamide riboside kinase 2, NRK 2, NmR-K 2, Integrin beta-1-binding protein 3, Muscle integrin-binding protein, MIBP, Nicotinic acid riboside kinase 2, Ribosylnicotinamide kinase 2, RNK 2, Ribosylnicotinic acid kinase 2, NMRK2, ITGB1BP3, NRK2

类别

常规抗体

推荐应用

反应种属

Human, Rat, Mouse

Human Gene ID

NP_733778.1

Human Swissprot No.

Q9NPI5

特异性

This ITGB1BP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 27-55 amino acids from the N-terminal region of human ITGB1BP3.

稀释度

WB~~1:1000;IHC-P~~1:100~500

预测分子量

26kDa

同种型

Rabbit Ig

背景介绍

ITGB1BP3 catalyzes the phosphorylation of nicotinamide riboside (NR) and nicotinic acid riboside (NaR) to form nicotinamide mononucleotide (NMN) and nicotinic acid mononucleotide (NaMN). The protein reduces laminin matrix deposition and cell adhesion to laminin, but not to fibronectin. It is involved in the regulation of PXN at the protein level and of PXN tyrosine phosphorylation and may play a role in the regulation of terminal myogenesis.

组织表达

Predominantly expressed in skeletal muscle and, at a much lower level, in the heart (at protein level). No expression in brain, kidney, liver, lung, pancreas nor placenta

期货

现货

纯化

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Western blot analysis of ITGB1BP3 Antibody (N-term) in K562 cell line lysates (35ug/lane). ITGB1BP3 (arrow) was detected using the purified Pab.

Formalin-fixed and paraffin-embedded human skeletal muscle tissue reacted with ITGB1BP3 antibody (N-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.