BD-PB2113-EXOSC8 Rabbit Polyclonal Antibody (C-term)-现货抗体产品库武汉枢密脑科学技术有限公司

EXOSC8 Rabbit Polyclonal Antibody (C-term)

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产品基本信息

产品货号

BD-PB2113

产品名称

EXOSC8 Rabbit Polyclonal Antibody (C-term)

别名

Exosome complex component RRP43, Exosome component 8, Opa-interacting protein 2, OIP-2, Ribosomal RNA-processing protein 43, p9, EXOSC8, OIP2, RRP43

类别

常规抗体

推荐应用

反应种属

Human

Human Gene ID

NP_852480.1

Human Swissprot No.

Q96B26

特异性

This EXOSC8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 243-276 amino acids from the C-terminal region of human EXOSC8.

稀释度

WB~~1:1000;IHC-P~~1:100~500;FC~~1:10~50

预测分子量

30kDa

同种型

Rabbit Ig

背景介绍

EXOSC8 is a component of the exosome 3'->5' exoribonuclease complex, a complex that degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3'-untranslated regions. It is required for the 3'-processing of the 7S pre-RNA to the mature 5.8S rRNA and has a 3'-5' exonuclease activity.

细胞定位

Cytoplasm. Nucleus. Nucleus, nucleolus

期货

现货

纯化

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Western blot analysis of anti-EXOSC8 Antibody (C-term) in HL60 cell line lysates (35ug/lane). EXOSC8(arrow) was detected using the purified Pab.

Formalin-fixed and paraffin-embedded human brain tissue with EXOSC8 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

EXOSC8 Antibody (C-term) flow cytometry analysis of HL-60 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.