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Arhgef9 Rabbit Polyclonal Antibody (Center)

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产品基本信息

产品货号
BD-PB2094
产品名称
Arhgef9 Rabbit Polyclonal Antibody (Center)
别名
Rho guanine nucleotide exchange factor 9, Collybistin, Rac/Cdc42 guanine nucleotide exchange factor 9, Arhgef9
类别
常规抗体
推荐应用
WB
反应种属
Rat
Human Swissprot No.
Q9QX73
Rat Gene ID
NP_076447.1
特异性
This Arhgef9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 274-303 amino acids from the Central region of human Arhgef9.
稀释度
WB~~1:1000;IHC-P~~1:100~500
预测分子量
58kDa
同种型
Rabbit Ig
背景介绍
ARHGEF9 belongs to a family of Rho-like GTPases that act as molecular switches by cycling from the active GTP-bound state to the inactive GDP-bound state. These proteins are key regulators of the actin cytoskeleton and are involved in cell signaling.
组织表达
Detected in brain, throughout the gray matter. Detected at low levels in heart and skeletal muscle
细胞定位
Cytoplasm. Cell junction, synapse, postsynaptic density {ECO:0000250|UniProtKB:Q3UTH8}
期货
现货
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

All lanes : Anti-Collybistin(Arhgef9) (Center) at 1:1000 dilution Lane 1: rat brain lysate Lane 2: rat heart lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 58 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

Formalin-fixed and paraffin-embedded human brain tissue reacted with Arhgef9 Antibody (Center) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

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