BD-PB2077-ZMPSTE24 Rabbit Polyclonal Antibody (C-term)-现货抗体产品库武汉枢密脑科学技术有限公司

ZMPSTE24 Rabbit Polyclonal Antibody (C-term)

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产品基本信息

产品货号

BD-PB2077

产品名称

ZMPSTE24 Rabbit Polyclonal Antibody (C-term)

别名

CAAX prenyl protease 1 homolog, Farnesylated proteins-converting enzyme 1, FACE-1, Prenyl protein-specific endoprotease 1, Zinc metalloproteinase Ste24 homolog, ZMPSTE24, FACE1, STE24

类别

常规抗体

推荐应用

反应种属

Human

Human Gene ID

NP_005848.2

Human Swissprot No.

O75844

特异性

This ZMPSTE24 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 440-470 amino acids from the C-terminal region of human ZMPSTE24.

稀释度

WB~~1:1000;IHC-P~~1:100~500

预测分子量

55kDa

同种型

Rabbit Ig

背景介绍

ZMPSTE24 is a zinc metalloprotease similar to yeast Ste24p. It is an integral membrane protein belonging to peptidase family M48 and is found in the endoplasmic reticulum and possibly in the Golgi compartment. It is thought to be involved in the proteolytic processing of farnesylated proteins.

组织表达

Widely expressed. High levels in kidney, prostate, testis and ovary

细胞定位

Endoplasmic reticulum membrane; Multi-pass membrane protein. Nucleus inner membrane; Multi-pass membrane protein

期货

现货

纯化

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

The anti-ZMPSTE24 Pab is used in Western blot to detect ZMPSTE24 in T-47D cell lysate.

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.