产品名称
LLGL2 Rabbit Polyclonal Antibody (C-term)
别名
Lethal(2) giant larvae protein homolog 2, HGL, LLGL2
Human Gene ID
NP_001015002.1;NP_001026973.1;NP_004515.2
Human Swissprot No.
Q6P1M3
特异性
This LLGL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 940-973 amino acids from the C-terminal region of human LLGL2.
背景介绍
The lethal (2) giant larvae protein of Drosophila plays a role in asymmetric cell division, epithelial cell polarity, and cell migration. LLGL2 is a protein similar to lethal (2) giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC). In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells.
细胞定位
Cytoplasm. Note=Localized in the perinuclear structure and faintly at the cell- cell contacts sites in the interphase. Localized at the cell periphery during metaphase. Cortical localization in mitotic cells. Found in the lateral region of polarized epithelial cells
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
