产品名称
MEX3C Rabbit Polyclonal Antibody (C-term)
别名
RNA-binding E3 ubiquitin-protein ligase MEX3C, 632-, RING finger and KH domain-containing protein 2, RING finger protein 194, MEX3C, RKHD2, RNF194
Human Gene ID
NP_057710.3
Human Swissprot No.
Q5U5Q3
特异性
This MEX3C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 536-564 amino acids from the C-terminal region of human MEX3C.
背景介绍
This gene encodes a member of a family of proteins with
two K homology (KH) RNA-binding domains and a C-terminal
RING-finger domain. The protein interacts with mRNA via the KH
domains, and the protein shuttles between the nucleus and
cytoplasm. Polymorphisms in this gene may contribute to
hypertension.
组织表达
Highest levels found in fetal brain and testis. Also expressed in thymus, salivary gland and uterus. Highly expressed in cells of the innate immune system, in particular activated NK cells Week expression in the intestine.
细胞定位
Cytoplasm. Nucleus. Note=Predominantly expressed in the cytoplasm and shuttles between the cytoplasm and the nucleus through the CRM1 export pathway. May act as suppressor of replication stress and chromosome missegregation
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
