BD-PB2034-Mouse Sike1 Rabbit Polyclonal Antibody (N-term)-现货抗体产品库武汉枢密脑科学技术有限公司

Mouse Sike1 Rabbit Polyclonal Antibody (N-term)

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产品基本信息

产品货号

BD-PB2034

产品名称

Mouse Sike1 Rabbit Polyclonal Antibody (N-term)

别名

Suppressor of IKBKE 1, Suppressor of IKK-epsilon, Sike1

类别

常规抗体

推荐应用

反应种属

Mouse

Human Swissprot No.

Q9CPR7

Mouse Gene ID

NP_079955.1

特异性

This Mouse Sike1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36-63 amino acids from the N-terminal region of mouse Sike1.

稀释度

WB~~1:1000

预测分子量

24kDa

同种型

Rabbit Ig

背景介绍

Physiological suppressor of IKK-epsilon and TBK1 that plays an inhibitory role in virus-and TLR3-triggered IRF3. Inhibits TLR3-mediated activation of interferon-stimulated response elements (ISRE) and the IFN-beta promoter. May act by disrupting the interactions of IKBKE or TBK1 with TICAM1/TRIF, IRF3 and DDX58/RIG-I. Does not inhibit NF-kappa-B activation pathways (By similarity).

细胞定位

Cytoplasm.

期货

现货

纯化

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Anti-MOUSE Sike1 Antibody (N-term) at 1:1000 dilution + mouse liver lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 24 kDa Blocking/Dilution buffer: 5% NFDM/TBST.