产品名称
FXR1 Rabbit Polyclonal Antibody (N-term)
别名
Fragile X mental retardation syndrome-related protein 1, hFXR1p, FXR1
Human Gene ID
NP_001013456.1;NP_001013457.1;NP_005078.2
Human Swissprot No.
P51114
特异性
This FXR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-66 amino acids from the N-terminal region of human FXR1.
背景介绍
The protein encoded by this gene is an RNA binding protein
that interacts with the functionally-similar proteins FMR1 and
FXR2. These proteins shuttle between the nucleus and cytoplasm and
associate with polyribosomes, predominantly with the 60S ribosomal
subunit. Three transcript variants encoding different isoforms have
been found for this gene.
组织表达
Expressed in all tissues examined including heart, brain, kidney and testis.
细胞定位
Cytoplasm, cytosol. Note=Adjacent to Z-lines in muscles {ECO:0000250|UniProtKB:Q61584}
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.