产品名称
RGS2 Rabbit Polyclonal Antibody (N-term)
别名
Regulator of G-protein signaling 2, RGS2, Cell growth-inhibiting gene 31 protein, G0/G1 switch regulatory protein 8, RGS2, G0S8
Human Gene ID
NP_002914.1
Human Swissprot No.
P41220
特异性
This RGS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 4-32 amino acids from the N-terminal region of human RGS2.
背景介绍
Regulator of G protein signaling (RGS) family members are
regulatory molecules that act as GTPase activating proteins (GAPs)
for G alpha subunits of heterotrimeric G proteins. RGS proteins are
able to deactivate G protein subunits of the Gi alpha, Go alpha and
Gq alpha subtypes. They drive G proteins into their inactive
GDP-bound forms. Regulator of G protein signaling 2 belongs to this
family. The protein acts as a mediator of myeloid differentiation
and may play a role in leukemogenesis.
组织表达
Expressed in acute myelogenous leukemia (AML) and in acute lymphoblastic leukemia (ALL).
细胞定位
[Isoform 1]: Cell membrane. Cytoplasm. Nucleus, nucleolus [Isoform 3]: Cell membrane. Cytoplasm Nucleus, nucleolus
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
