BD-PB2023-Mouse Txnip Rabbit Polyclonal Antibody (Center)-现货抗体产品库武汉枢密脑科学技术有限公司

Mouse Txnip Rabbit Polyclonal Antibody (Center)

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产品基本信息

产品货号

BD-PB2023

产品名称

Mouse Txnip Rabbit Polyclonal Antibody (Center)

别名

Thioredoxin-interacting protein, Vitamin D3 up-regulated protein 1, Txnip, Vdup1

类别

常规抗体

推荐应用

反应种属

Human, Rat, Mouse

Human Swissprot No.

Q8BG60

Mouse Gene ID

NP_001009935.1;NP_076208.2

特异性

This Mouse Txnip antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 116-145 amino acids from the Central region of mouse Txnip.

稀释度

IHC-P~~1:100;WB~~1:2000

预测分子量

44kDa

同种型

Rabbit Ig

背景介绍

May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells.

组织表达

Ubiquitously expressed.

细胞定位

Cytoplasm.

期货

现货

纯化

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunohistochemical analysis of BD-PB2023 on paraffin-embedded Mouse liver tissue. Tissue was fixed with formaldehyde at room temperature. Heat induced epitope retrieval was performed by EDTA buffer (pH9. 0). Samples were incubated with primary antibody(1:100) for 1 hour at room temperature. Undiluted CRF Anti-Polyvalent HRP Polymer antibody was used as the secondary antibody.

Anti-Mouse Txnip Antibody (Center) at 1:2000 dilution + Mouse stomach tissue lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 44 kDa Blocking/Dilution buffer: 5% NFDM/TBST.