BD-PB1997-FXN Rabbit Polyclonal Antibody (N-term)-现货抗体产品库武汉枢密脑科学技术有限公司

FXN Rabbit Polyclonal Antibody (N-term)

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产品基本信息

产品货号

BD-PB1997

产品名称

FXN Rabbit Polyclonal Antibody (N-term)

别名

Frataxin, mitochondrial, Friedreich ataxia protein, Fxn, Frataxin intermediate form, i-FXN, Frataxin(56-210), m56-FXN, Frataxin(78-210), d-FXN, m78-FXN, Frataxin mature form, Frataxin(81-210), m81-FXN, FXN, FRDA, X25

类别

常规抗体

推荐应用

反应种属

Human

Human Gene ID

NP_000135.2;NP_001155178.1;NP_852090.1

Human Swissprot No.

Q16595

特异性

This FXN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36-64 amino acids from the N-terminal region of human FXN.

稀释度

WB~~1:1000

预测分子量

23kDa

同种型

Rabbit Ig

背景介绍

This nuclear gene encodes a mitochondrial protein which belongs to FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA results in Friedreich ataxia. Alternative splicing results in multiple transcript variants.

组织表达

Expressed in the heart, peripheral blood lymphocytes and dermal fibroblasts.

细胞定位

Mitochondrion. Cytoplasm, cytosol. Note=PubMed:18725397 reports localization exclusively in mitochondria.

期货

现货

纯化

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Anti-FXN Antibody (N-term) at 1:1000 dilution + CCRF-CEM whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 23 kDa Blocking/Dilution buffer: 5% NFDM/TBST.