产品名称
HIST2H2AC Rabbit Polyclonal Antibody (Center)
别名
Histone H2A type 2-C, Histone H2A-GL101, Histone H2A/q, HIST2H2AC, H2AFQ
Human Gene ID
NP_003508.1
Human Swissprot No.
Q16777
特异性
This HIST2H2AC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 18-46 amino acids from the Central region of human HIST2H2AC.
背景介绍
Histones are basic nuclear proteins that are responsible
for the nucleosome structure of the chromosomal fiber in
eukaryotes. Two molecules of each of the four core histones (H2A,
H2B, H3, and H4) form an octamer, around which approximately 146 bp
of DNA is wrapped in repeating units, called nucleosomes. The
linker histone, H1, interacts with linker DNA between nucleosomes
and functions in the compaction of chromatin into higher order
structures. This gene is intronless and encodes a member of the
histone H2A family.
细胞定位
Nucleus. Chromosome.
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.