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HDBP2(HDRF-2) Rabbit Polyclonal Antibody (Center)

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产品基本信息

产品货号
BD-PB1977
产品名称
HDBP2(HDRF-2) Rabbit Polyclonal Antibody (Center)
别名
Zinc finger protein 395, HD-regulating factor 2, HDRF-2, Huntington disease gene regulatory region-binding protein 2, HD gene regulatory region-binding protein 2, HDBP-2, Papillomavirus regulatory factor 1, PRF-1, Papillomavirus-binding factor, ZNF395, HDBP2, PBF
类别
常规抗体
推荐应用
WB
反应种属
Human
Human Gene ID
NP_061130.1
Human Swissprot No.
Q9H8N7
特异性
This HDBP2(HDRF-2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 141-170 amino acids from the Central region of human HDBP2(HDRF-2).
稀释度
WB~~1:1000;IHC-P~~1:100~500
预测分子量
55kDa
同种型
Rabbit Ig
背景介绍
Papillomavirus Regulatory Factor 1/HDBP2 is a novel transcription factor shuttling between nucleus and cytoplasm and binds to the specific GCCGGCG, which is an essential cis-element for Huntington's disease gene expression.
组织表达
Widely expressed.
细胞定位
Cytoplasm. Nucleus. Note=May shuttle between nucleus and cytoplasm
期货
现货
纯化
Purified rabbit polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Western blot analysis of anti-HDBP2(HDRF-2) Antibody (Center) in Y79 cell line lysates (35ug/lane). HDBP2(arrow) was detected using the purified Pab.

Formalin-fixed and paraffin-embedded human Hepatocellular carcinoma reacted with anti-HDBP2(HDRF-2) Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

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