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Importin alpha-3 (KPNA4)Rabbit Polyclonal Antibody (C-term)

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产品基本信息

产品货号
BD-PB1964
产品名称
Importin alpha-3 (KPNA4)Rabbit Polyclonal Antibody (C-term)
别名
Importin subunit alpha-3, Importin alpha Q1, Qip1, Karyopherin subunit alpha-4, KPNA4, QIP1
类别
常规抗体
推荐应用
WB
反应种属
Human, Mouse
Human Gene ID
NP_002259.1
Human Swissprot No.
O00629
特异性
This Importin alpha-4 (KPNA4) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the C-terminal region of human Importin alpha-4 (KPNA4).
稀释度
WB~~1:1000
预测分子量
58kDa
同种型
Rabbit Ig
背景介绍
The nuclear import of karyophilic proteins is directed by short amino acid sequences termed nuclear localization signals (NLSs). Karyopherins, or importins, are cytoplasmic proteins that recognize NLSs and dock NLS-containing proteins to the nuclear pore complex. The protein encoded by this gene shares the sequence similarity with Xenopus importin-alpha and Saccharomyces cerevisiae Srp1. This protein is found to interact with the NLSs of DNA helicase Q1 and SV40 T antigen.
组织表达
Highly expressed in testis, ovary, small intestine, heart, skeletal muscle, lung and pancreas, but barely detectable in kidney, thymus, colon and peripheral blood leukocytes
细胞定位
Cytoplasm. Nucleus.
期货
现货
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

The anti-Importin alpha-4 Pab is used in Western blot to detect Importin alpha-4 in Hela (left), mouse brain (middle), and HepG2 (right)cell line/tissue lysates.

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