产品名称
DNAJB12 Rabbit Polyclonal Antibody(N-term)
别名
DnaJ homolog subfamily B member 12, DNAJB12
Human Gene ID
NP_001002762.2;NP_060096.3
Human Swissprot No.
Q9NXW2
特异性
This DNAJB12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 7-36 amino acids from the N-terminal region of human DNAJB12.
背景介绍
DNAJB12 belongs to the evolutionarily conserved DNAJ/HSP40
family of proteins, which regulate molecular chaperone activity by
stimulating ATPase activity. DNAJ proteins may have up to 3
distinct domains: a conserved 70-amino acid J domain, usually at
the N terminus; a glycine/phenylalanine (G/F)-rich region; and a
cysteine-rich domain containing 4 motifs resembling a zinc finger
domain (Ohtsuka and Hata, 2000 [PubMed 11147971]).[supplied by
OMIM].
细胞定位
Endoplasmic reticulum membrane; Single-pass membrane protein. Nucleus membrane; Single-pass membrane protein. Note=Localizes to the endoplasmic reticulum membrane (PubMed:21150129, PubMed:21148293, PubMed:24732912, PubMed:27916661) When overexpressed, forms membranous structures in the nucleus (PubMed:24732912).
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
