产品名称
RM02 Rabbit Polyclonal Antibody
蛋白名称
39S ribosomal protein L2, mitochondrial (L2mt) (MRP-L2)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q5T653
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q5T653/entry
Mouse Swissprot No.
Q9D773
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9D773
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q498T4
免疫原
Synthesized peptide derived from human protein . at AA range: 210-290
特异性
RM02 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the EcoL2 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 12q. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
功能
similarity:Belongs to the ribosomal protein L2P family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.