产品名称
Mouse Ephb6 Rabbit Polyclonal Antibody(Center)
别名
Ephrin type-B receptor 6, MEP, Tyrosine-protein kinase-defective receptor EPH-6, Ephb6, Cekl
Human Swissprot No.
O08644
Mouse Gene ID
NP_001139823.1;NP_031706.3
特异性
This Mouse Ephb6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 503-530 amino acids from the Central region of mouse Ephb6.
背景介绍
Kinase-defective receptor for members of the ephrin-B family. Binds to ephrin-B1 and ephrin-B2. Modulates cell adhesion and migration by exerting both positive and negative effects upon stimulation with ephrin-B2. Inhibits JNK activation, T cell receptor-induced IL-2 secretion and CD25 expression upon stimulation with ephrin-B2 (By similarity).
组织表达
High level in thymus, and brain. Very low levels of expression in kidney, lung, liver, bone marrow, skeletal muscle, spleen from 2 week old and adult mice, heart, testes and embryonic stem cells
细胞定位
[Isoform 1]: Cell membrane; Single-pass type I membrane protein [Isoform 3]: Secreted.
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
