产品名称
SLC30A10 Rabbit Polyclonal Antibody (C-term)
别名
Zinc transporter 10, ZnT-10, Solute carrier family 30 member 10, SLC30A10, ZNT10, ZNT8
Human Gene ID
NP_061183.2
Human Swissprot No.
Q6XR72
特异性
This SLC30A10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 331-359 amino acids from the C-terminal region of human SLC30A10.
背景介绍
Zinc functions as a cofactor for numerous enzymes, nuclear
factors, and hormones and as an intra- and intercellular signal
ion. Members of the zinc transporter (ZNT)/SLC30 subfamily of the
cation diffusion facilitator family, such as SLC30A10, permit
cellular efflux of zinc (Seve et al., 2004 [PubMed
15154973]).
组织表达
Specifically expressed in fetal liver and fetal brain (PubMed:15154973). Expressed in adult tissues with relative levels small intestine > liver > testes > brain > ovary > colon > cervix > prostate > placenta (PubMed:22706290)
细胞定位
Cell membrane; Multi-pass membrane protein. Golgi apparatus, trans-Golgi network. Recycling endosome. Early endosome. Note=Relocalized from the trans-Golgi network to the plasma membrane upon elevated extracellular Zn concentrations (PubMed:22706290).
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
