产品名称
TBX4 Rabbit Polyclonal Antibody (N-term)
别名
T-box transcription factor TBX4, T-box protein 4, TBX4
Human Gene ID
NP_060958.2
Human Swissprot No.
P57082
特异性
This TBX4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 103-129 amino acids from the N-terminal region of human TBX4.
背景介绍
This gene is a member of a phylogenetically conserved
family of genes that share a common DNA-binding domain, the T-box.
T-box genes encode transcription factors involved in the regulation
of developmental processes. This gene is the human homolog of mouse
Tbx4, which is closely linked to Tbx2 on mouse chromosome 11.
Similarly this gene, like TBX2, maps to human chromosome 17.
Expression studies in mouse and chicken show that Tbx4 is expressed
in developing hindlimb, but not in forelimb buds, suggesting a role
for this gene in regulating limb development and specification of
limb identity.
细胞定位
Nucleus {ECO:0000255|PROSITE-ProRule:PRU00201}.
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
