产品名称
ITPA Rabbit Polyclonal Antibody (C-term)
别名
Inosine triphosphate pyrophosphatase {ECO:0000255|HAMAP-Rule:MF_03148}, ITPase {ECO:0000255|HAMAP-Rule:MF_03148}, Inosine triphosphatase {ECO:0000255|HAMAP-Rule:MF_03148}, 36119 {ECO:0000255|HAMAP-Rule:MF_03148}, Non-canonical purine NTP pyrophosphatase {ECO:0000255|HAMAP-Rule:MF_03148}, Non-standard purine NTP pyrophosphatase {ECO:0000255|HAMAP-Rule:MF_03148}, Nucleoside-triphosphate diphosphatase {ECO:0000255|HAMAP-Rule:MF_03148}, Nucleoside-triphosphate pyrophosphatase {ECO:0000255|HAMAP-Rule:MF_03148}, NTPase {ECO:0000255|HAMAP-Rule:MF_03148}, Putative oncogene protein hlc14-06-p, ITPA {ECO:0000255|HAMAP-Rule:MF_03148}, C20orf37
Human Gene ID
NP_001254552.1;NP_258412.1;NP_852470.1
Human Swissprot No.
Q9BY32
特异性
This ITPA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 149-178 amino acids from the C-terminal region of human ITPA.
背景介绍
The protein encoded by this gene hydrolyzes inosine
triphosphate and deoxyinosine triphosphate to the monophosphate
nucleotide and diphosphate. The encoded protein, which is a member
of the HAM1 NTPase protein family, is found in the cytoplasm and
acts as a homodimer. Defects in the encoded protein can result in
inosine triphosphate pyrophosphorylase deficiency. Two transcript
variants encoding two different isoforms have been found for this
gene. Also, at least two other transcript variants have been
identified which are probably regulatory rather than
protein-coding.
组织表达
Ubiquitous. Highly expressed in heart, liver, sex glands, thyroid and adrenal gland
细胞定位
Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03148, ECO:0000269|PubMed:11278832}
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
