产品名称
RT15 Rabbit Polyclonal Antibody
蛋白名称
28S ribosomal protein S15, mitochondrial (MRP-S15) (S15mt)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
P82914
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P82914/entry
Mouse Swissprot No.
Q9DC71
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9DC71
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q5XI37
免疫原
Synthesized peptide derived from human protein . at AA range: 80-160
特异性
RT15 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S15P family. The encoded protein is more than two times the size of its E. coli counterpart, with the 12S rRNA binding sites conserved. Between human and mouse, the encod
组织表达
Aorta endothelial cell,Dendritic cell,Skin,
功能
similarity:Belongs to the ribosomal protein S15P family.,subunit:Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30 distinct proteins.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.