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G2E3 Rabbit Polyclonal Antibody (Center)

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产品基本信息

产品货号
BD-PB1849
产品名称
G2E3 Rabbit Polyclonal Antibody (Center)
别名
G2/M phase-specific E3 ubiquitin-protein ligase, 632-, G2E3, KIAA1333
类别
常规抗体
推荐应用
WB
反应种属
Human
Human Gene ID
NP_060239.2
Human Swissprot No.
Q7L622
特异性
This G2E3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 226-252 amino acids from the Central region of human G2E3.
稀释度
WB~~1:2000
预测分子量
81kDa
同种型
Rabbit Ig
背景介绍
E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Essential in early embryonic development to prevent apoptotic death.
组织表达
Predominantly expressed in brain, liver, kidney, testes and ovary.
细胞定位
Nucleus, nucleolus. Cytoplasm. Note=Shuttles between the nucleus and the cytoplasm. In the nucleus, delocalizes from the nucleolus to the nucleoplasm in response to DNA damage
期货
现货
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

All lanes : Anti-G2E3 Antibody (Center) at 1:2000 dilution Lane 1: Hela whole cell lysate Lane 2: 293T/17 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 81 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

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